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    Multivariate Experiments > Assay Development

    Faster and better
    assay development.

    Assay development underpins the success of discovery programmes. Modern challenges call for better experiments, and Synthace Discovery is the dedicated, end-to-end solution that enables assay teams to stay ahead.

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    Assay quality

    Optimize for different goals

    Use Synthace Discovery to find the best version of the assay you are working on.

    Whether you want to decrease the noise, boost the signal, cut costs, or make an assay more robust, explore powerful multivariate experimental designs to unpick interactions between factors and find the sweet spot.

    Assay plate layout, coloured by hte concentrations of different components
    Automatic calculations

    Stock concentrations are seamlessly calculated

    Testing many combinations of multiple liquids in very small volumes makes it a challenge to find the stock concentrations that are needed, as you easily reach limits for an accurate transfer. 

    With Synthace, stock concentrations are determined automatically for each liquid, taking into account the design, the plate, and the device that is used. No more trial-and-error in complicated spreadsheets.

    Experiment simulation with Synthace Discovery
    Easy automation

    Generate device instructions, automatically

    Synthace Discovery translates DOE and HDE designs into the accurate automation instructions needed for assay optimization. 

    There's no need to convert concentrations into volumes into device instructions. If you have a design, you’re able to fully automate your experiment, across different devices, with Synthace Discovery.

    Measurement over substrate concentration showing 4PL model fit.
    Data analysis

    Structure and analyze your data in context

    By capturing the experimental design and structure, Synthace can easily structure your data, even if the response you are modelling is calculated from multiple datapoints.

    In Synthace, you can easily define a DOE that defines multiple buffer conditions, create a dose response curve for each one, with replicates, estimate XC50 or other quantities, and use those values as responses when model building.

    “Using Synthace DOE has changed the way we do experiments, but more interestingly the way we think and communicate.”

    Helena Peilot Sjögren | Principal Scientist, AstraZeneca