Technical Note: Enhancing RoboColumn® Workflows with Synthace and Te-Chrom™

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Study summary
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We compared miniaturized purification using two software platforms: Tecan’s Freedom EVOware® Te-Chrom™ Wizard and Synthace's cloud-based software.
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We used both platforms to generate instructions for liquid handling robots for purification of IgG from human serum using MabSelect™ PrismA RoboColumns®.

Key findings
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• Equivalence between Synthace and Freedom EVOware® generated instructions
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• Significant time savings with Synthace's data structuring and visualization functionalities, blanks are easily specified and automatically used in data correction
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• Enhanced flexibility with Synthace, e.g. specifying multiple buffers within individual chromatography stages

80%

Reduction in data processing, visualization and analysis time

50%

Saving in time spent adapting experimental design between runs

58%

Time saving in selecting, pooling, and normalizing samples

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